SITE OF ORIGIN OF A HYPERGLYCEMIC SUBSTANCE LIBERATED INTO THE PANCREATO-DUODENAL BLOOD BY DESERPIDINE INJECTIONS1
- 1 August 1960
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 67 (2) , 248-251
- https://doi.org/10.1210/endo-67-2-248
Abstract
The injection of deserpidine into the pancreato-duodenal artery of normal dogs is followed by a prompt rise in blood sugar concentration. This hyperglycemia is not observed in previously de-pancreatized dogs. The results suggest that deserpidine causes the release of a hyperglycemic substance originating in the pancreas. The nature of this substance is unknown, although it appears to be different from the hyperglycemic material released by the injection of growth hormone.Keywords
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