FURTHER STUDIES ON THE CONTROL OF MENORRHAGIA

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Abstract
THE successful approach to the management of menorrhagia is clouded by the vast number of therapeutic measures advocated in the past. Their number is legion and runs the gamut from the speculative administration of various drugs and endocrine preparations to the coup de grace of the fatalist; to wit, hysterectomy. During the past decade the literature concerned with the organic therapy of functional uterine bleeding has been extensive and the promulgated methods have ranged from the administration of the time honored remedy of extract of ergot to the use of snake venom (37), vitamin B therapy (4), thyroid, the various gonadotrophic preparations, blood from lactating women (13, 14), prolactin (11, 19, 30) and, finally, any one of the various sex sterols, either singly or in cpmbination. Inasmuch as our present knowledge of menstruation implies that it is directly under the control of the steroid hormones of the ovary, it is logical to assume that therapeutic measures to correct excessive uterine bleeding should involve the judicious use of these same steroids.

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