INFLUENCE OF HYDROCORTISONE (COMPOUND F) ON MAST CELLS OF NORMAL SKIN AND HEALING WOUNDS IN THE RABBIT
- 1 August 1954
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 16 (4) , 300-304
- https://doi.org/10.1530/acta.0.0160300
Abstract
The effect of intradermally administered hydrocortisone on rabbit mast cells was studied in 63 biopsies and compared with the effect of intradermally administered cortisone, cholesterol and saline solution. Hydrocortisone and cortisone produced alterations in the morphology of the mast cells similar to those observed during systemic cortisone therapy, the most striking change being the inequality in shape and size of the granules. It was thought that both compounds acted directly upon the individual cells. There was no distinct effect upon the fibroblasts, and wound healing was not significantly delayed.Keywords
This publication has 13 references indexed in Scilit:
- Cortisone on Oxygen Consumption of Granulation Tissue from the RabbitExperimental Biology and Medicine, 1953
- Free Wandering Cells and CortisoneExperimental Biology and Medicine, 1953
- Effect of Some Steroids and of Corticotropin (ACTH) on Cellular ActivityExperimental Biology and Medicine, 1953
- Use of "Granuloma Pouch" Technic in the Study of Antiphlogistic CorticoidsExperimental Biology and Medicine, 1953
- HORMONAL INTERACTION IN THE REGULATION OF GRANULATION TISSUE FORMATIONEndocrinology, 1952
- The Mast Cell. Cortisone Action on Connective TissueExperimental Biology and Medicine, 1952
- OBSERVATIONS ON THE INFLUENCE OF CORTISONE ON TISSUE RESPONSE TO INJURY1952
- Influence of Cortisone upon Acute Inflammation.Experimental Biology and Medicine, 1952
- Effect of Cortisone on the Mast Cells of the RatExperimental Biology and Medicine, 1951
- INTERFERENCE WITH WOUND HEALING BY THE LOCAL ACTION OF ADRENOCORTICAL STEROIDS1Endocrinology, 1950