EARLY EFFECTS OF FASTING AND OF CARBOHYDRATE INGESTION ON LIPIDS AND LIPOPROTEINS OF SERUM IN MAN

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Abstract
Concentrations of chemical constituents of ultracentrifugally separated serum lipoprotein fractions were measured in healthy adults for several hours after ingestion of 400 g of glucose and during a comparable period of fasting. A 12- to 15-hour fast preceded each period. All lipid constituents of very low density (< 1.019) lipoproteins fell consistently after glucose, but showed no consistent change during continued fasting. No consistent change occurred in low density (1.019-1.063) lipoproteins. High density (1.063-1.21) lipoprotein phospholipids rose slightly during continued fasting and fell during the period following glucose with no comparable change in other constituents. The concentration of very low density serum lipoprotein constituents is related to the availability of glucose for energy production.