SERUM PRECIPITABLE IODINE CONCENTRATIONS DURING PREGNANCY 1
Open Access
- 1 January 1948
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 27 (1) , 91-97
- https://doi.org/10.1172/jci101928
Abstract
Serum precipitable iodines of 43 pregnant [female] [female] have been measured during pregnancy and in 11 instances after delivery. In 29 normal pregnancies, serum precipitable iodines ranged between 6.2 and 11.2 y %, the normal non-pregnant range being 4.0-8.0 7 %. This elevation of serum precipitable iodine was noted as early as 3 wks. after conception, did not increase as pregnancy advanced and decreased rapidly to the normal range after delivery. Elevated serum precipitable iodines are physiologic for normal pregnancies; they do not indicate hyperthyroidism. In some patients who threatened to abort, or actually aborted, serum precipitable iodines were between 2.8 and 5.8 y %. In such instances, the admn. of desiccated thyroid should be considered. Thyroid medication for infertility appears to be indicated only in hypothyroid patients. Hyperthyroidism of 4 pregnant [female] [female] was controlled easily and pregnancy maintained with Lugol''s soln. alone, or in conjunction with small amts. of thiourea.Keywords
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