Secondary metabolites by chemical screening. II. Amycins A and B, two novel niphimycin analogs isolated from a high producer strain of elaiophylin and nigericin.
- 1 January 1990
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 43 (6) , 639-647
- https://doi.org/10.7164/antibiotics.43.639
Abstract
Two novel natural niphimycin analogs, amycins A (5) and B (3) were isolated from the culture broth of the Streptomyces sp. DSM 3816 by chemical screening methods. In addition this strain produces the antibiotics niphimycin (4), elaiophylin (21) and nigericin (1). Fermentation, isolation, structure elucidation and biological activity of the amycins are described.This publication has 15 references indexed in Scilit:
- Isolation of neocopiamycin A from Streptomyces hygroscopicus var. crystallogenes, the copiamycin source.The Journal of Antibiotics, 1984
- Novel synergism of two antifungal agents, copiamycin and imidazoleAntimicrobial Agents and Chemotherapy, 1983
- Stoffwechselprodukte von Mikroorganismen. 219. Mitteilung. Versuche zur Strukturaufklärung von Niphimycin, 2. Teil. Die Konstitution von Desmalonyl‐niphimycin IHelvetica Chimica Acta, 1983
- Stoffwechselprodukte von Mikroorganismen. 218. Mitteilung. Versuche zur Strukturaufklärung von Niphimycin, 1. Teil. Reinigung und Charakterisierung der Niphimycine Iα und Iβ sowie Abbau mit SalpetersäureHelvetica Chimica Acta, 1983
- Structure of scopafungin, a potent nonpolyene antifungal antibioticJournal of the American Chemical Society, 1982
- Stoffwechselprodukte von Mikroorganismen. 211. Milteilung. Röntgenstrukturanalyse von ElaiophylinHelvetica Chimica Acta, 1982
- Studies on macrocyclic lactone antibiotics. VI. Skeletal structure of copiamycin.The Journal of Antibiotics, 1982
- 2-ethyl-5-(3-indolyl)oxazole from Streptomyces cinnamomeus discovered by chemical screening. Characterization and structure elucidation by X-ray analysis.The Journal of Antibiotics, 1982
- Stoffwechselprodukte von Mikroorganismen. 202. Mitteilung. Strukturaufklärung von Elaiophylin: Spektroskopische Untersuchungen und AbbauHelvetica Chimica Acta, 1981
- Metabolic products of microorganisms. 200. Isolation and characterization of niphithricins A, B, and elaiophylin, antibiotics produced by Streptomyces violaceoniger.The Journal of Antibiotics, 1981