Effect of Histamine in Beeswax-Sesame Oil Mixture on Canine External Pancreatic Secretion and on the Resistance of Duodenal Mucosa to Trauma

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Abstract
Intramusc. injn. provokes a profuse secretion of canine pancreatic juice which flows at a constant rate and continues for at least 24 hrs. The duodenal mucosa, continuously subjected under these circumstances to contents with a pH between 1 and 2, rapidly becomes friable and quickly ulcerates when subjected to trauma which has no apparent effect under ordinary conditions.

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