THE PRESENCE OF A »GONADOTROPHIN INHIBITING SUBSTANCE« IN PINEAL GLAND EXTRACTS

Abstract
A bovine pineal gland extract was found to inhibit the stimulatory effect of both human chorionic gonadotropin (HCG) and human menopausal gonadotropin (HMG) on mouse uterine weight, while melatonin displayed no such inhibitory activity. The pineal gland extract did not inhibit the stimulatory effect of estrone.